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Biological Sciences

Biological Sciences

James G. Patton, Ph.D.

Stevenson Professor of Biological Sciences
Professor of Biological Sciences, Professor of Biochemistry, Director of Interdisciplinary Graduate Program

Specializations

Regulation of gene expression at the RNA level including microRNAs in development and disease; RNA interference, and alternative splicing.



Abstracts from PubMed

results for: James Patton Vanderbilt

Hinger, SA, Cha, DJ, Franklin, JL, Higginbotham, JN, Dou, Y, Ping, J, Shu, L, Prasad, N, Levy, S, Zhang, B, Liu, Q, Weaver, AM, Coffey, RJ, Patton, JG Diverse Long RNAs Are Differentially Sorted into Extracellular Vesicles Secreted by Colorectal Cancer Cells
Pinhal, D, Bovolenta, LA, Moxon, S, Oliveira, AC, Nachtigall, PG, Acencio, ML, Patton, JG, Hilsdorf, AWS, Lemke, N, Martins, C Genome-wide microRNA screening in Nile tilapia reveals pervasive isomiRs' transcription, sex-biased arm switching and increasing complexity of expression throughout development
Lu, Y, Zhao, X, Liu, Q, Li, C, Graves-Deal, R, Cao, Z, Singh, B, Franklin, JL, Wang, J, Hu, H, Wei, T, Yang, M, Yeatman, TJ, Lee, E, Saito-Diaz, K, Hinger, S, Patton, JG, Chung, CH, Emmrich, S, Klusmann, JH, Fan, D, Coffey, RJ lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling
Abramson, RG, McGhee, CR, Meyn, SM, Coleman, K, Gomillion, J, Beller, M, Fry, J, Bauer, GA, Knuutila, RJ, Pierce, R, Patton, JA, Omary, RA Building a Hospital Core Resource for Clinical Research Imaging: Lessons for Driving Change Within Complex Organizations
Kara, N, Wei, C, Commanday, AC, Patton, JG miR-27 regulates chondrogenesis by suppressing focal adhesion kinase during pharyngeal arch development
Flynt, AS, Rao, M, Patton, JG Blocking Zebrafish MicroRNAs with Morpholinos
Rao, MB, Didiano, D, Patton, JG Neurotransmitter-Regulated Regeneration in the Zebrafish Retina
Dou, Y, Cha, DJ, Franklin, JL, Higginbotham, JN, Jeppesen, DK, Weaver, AM, Prasad, N, Levy, S, Coffey, RJ, Patton, JG, Zhang, B Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes
Khuansuwan, S, Clanton, JA, Dean, BJ, Patton, JG, Gamse, JT A transcription factor network controls cell migration and fate decisions in the developing zebrafish pineal complex
Broadus, MR, Chen, TW, Neitzel, LR, Ng, VH, Jodoin, JN, Lee, LA, Salic, A, Robbins, DJ, Capobianco, AJ, Patton, JG, Huppert, SS, Lee, E Identification of a Paralog-Specific Notch1 Intracellular Domain Degron
McKenzie, AJ, Hoshino, D, Hong, NH, Cha, DJ, Franklin, JL, Coffey, RJ, Patton, JG, Weaver, AM KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes
Patton, JG, Franklin, JL, Weaver, AM, Vickers, K, Zhang, B, Coffey, RJ, Ansel, KM, Blelloch, R, Goga, A, Huang, B, L'Etoille, N, Raffai, RL, Lai, CP, Krichevsky, AM, Mateescu, B, Greiner, VJ, Hunter, C, Voinnet, O, McManus, MT Biogenesis, delivery, and function of extracellular RNA
Cha, DJ, Franklin, JL, Dou, Y, Liu, Q, Higginbotham, JN, Demory Beckler, M, Weaver, AM, Vickers, K, Prasad, N, Levy, S, Zhang, B, Coffey, RJ, Patton, JG KRAS-dependent sorting of miRNA to exosomes
Yin, L, Maddison, LA, Li, M, Kara, N, LaFave, MC, Varshney, GK, Burgess, SM, Patton, JG, Chen, W Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs
Olena, AF, Rao, MB, Thatcher, EJ, Wu, SY, Patton, JG miR-216a regulates snx5, a novel notch signaling pathway component, during zebrafish retinal development
Rajaram, K, Summerbell, ER, Patton, JG Technical brief: Constant intense light exposure to lesion and initiate regeneration in normally pigmented zebrafish
Rajaram, K, Harding, RL, Bailey, T, Patton, JG, Hyde, DR Dynamic miRNA expression patterns during retinal regeneration in zebrafish: reduced dicer or miRNA expression suppresses proliferation of Müller glia-derived neuronal progenitor cells
Andrews, OE, Cha, DJ, Wei, C, Patton, JG RNAi-mediated gene silencing in zebrafish triggered by convergent transcription
Rajaram, K, Harding, RL, Hyde, DR, Patton, JG miR-203 regulates progenitor cell proliferation during adult zebrafish retina regeneration
Noto, JM, Piazuelo, MB, Chaturvedi, R, Bartel, CA, Thatcher, EJ, Delgado, A, Romero-Gallo, J, Wilson, KT, Correa, P, Patton, JG, Peek, RM Strain-specific suppression of microRNA-320 by carcinogenic Helicobacter pylori promotes expression of the antiapoptotic protein Mcl-1