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David Cliffel

Professor of Chemistry
Cornelius Vanderbilt Chair & Director of Graduate Studies

Dr. Cliffel will be accepting graduate students for Fall 2025.


Joshua M. Passantino, Kody D. Wolfe, Keiann T. Simon, David E. Cliffel, and G. Kane Jennings. Photosystem I Enhances the Efficiency of a Natural, Gel-Based Dye-Sensitized Solar Cell. ACS Appl. Bio Mater. 2020, 3, 4465−4473.

Dhruba K. Pattadar, Rafael A. Masitas, Christopher D. Stachurski, David E. Cliffel, and Francis P. Zamborini. Reversing the Thermodynamics of Galvanic Replacement Reactions by Decreasing the Size of Gold Nanoparticles. J. Am. Chem. Soc.2020, 142, 45, 19268–19277.

Christopher D. Stachurski, Sophia M. Click, Kody D. Wolfe, Dilek Dervishogullari, Sandra J. Rosenthal, G. Kane Jennings, and David E. Cliffel Optical and electrochemical tuning of hydrothermally synthesized nitrogen-doped carbon dot. Nanoscale Adv., 2020, 2, 3375-3383.

Sara L. Melow, Dusty R. Miller, Evan A. Gizzie and David E. Cliffel. A low-interference, high-resolution multianalyte electrochemical biosensor  Anal. Methods , 2020,12, 3873-3882.

Kody D. Wolfe, Dilek Dervishogullari, Christopher D. Stachurski, Joshua M. Passantino, Dr. G. Kane Jennings, Dr. David E. Cliffel.   Photosystem I Multilayers within Porous Indium Tin Oxide Cathodes Enhance Mediated Electron Transfer. ChemElectroChem, 2020, 7(3), 596-603.

Kody D. Wolfe, Dilek Dervishogullari, Joshua M. Passantino, Christopher D. Stachurski, G. Kane Jennings and David E. Cliffel. Improving the stability of photosystem I–based bioelectrodes for solar energy conversion.  Current Opinions in Electrochemistry. 2020, 19, 27-34.

P. Mason McClatchey, Ethan S. McClain, Ian M. Williams, Carlo M. Malabanan, Freyja D. James, Peter C. Lord, Justin M. Gregory, David E. Cliffel, David H. Wasserman.  Fibrotic Encapsulation is the Dominant Source of Continuous Glucose Monitor Delays.  Diabetes 2019; 68(10): 1892-1901, DOI: 10.2337/db19-0229 

Dilek Dervishogullari, Evan A. Gizzie, G. Kane Jennings, David E. Cliffel. Polyviologen as Electron Transport Material in Photosystem I-Based Biophotovoltaic Cells. Langmuir, 2018, 34 (51), 15658-15664.

Dusty R. Miller, Ethan S. McClain, and David E. Cliffel. Electrochemical Microphysiometry Detects Cellular Glutamate Uptake. J. Electrochem. Soc. 2018 165:G3120-G3124; doi:10.1149/2.0201812jes

Maxwell T. Robinson, Marie E. Armbruster, Avi Gargye, David E. Cliffel, and G. Kane Jennings. Photosystem I Multilayer Films for Photovoltage Enhancement in Natural Dye-Sensitized Solar Cells, ACS Applied Energy Materials (2018), 1, 301-305. DOI: 10.1021/acsaem.7b00230.

Maxwell T. Robinson, David E. Cliffel, and G. Kane Jennings. An Electrochemical Reaction-Diffusion Model of the Photocatalytic Effect of Photosystem I Multilayer Films. Journal of Physical Chemistry B(2018) 122 (1), 117-125

McClatchey, P.M.; McClain, E.S.; Williams, I.M.; Malabanan, C.M.;  James, F.D.; Lord, P.C.; Gregory, J.M.; Cliffel, D.E.; Wasserman, D.H. Fibrotic Encapsulation Is the Dominant Source of Continuous Glucose Monitor Delays Diabetes  2019 Oct;  68 (10):  1892-1901.

Dervishogullari, D;  Gizzie, E.A.;  Jennings, G.K.;  Cliffel, D.E.; Polyviologen as Electron Transport Material in Photosystem I-Based Biophotovoltaic Cells Langmuir  2018, 34, 51, 15658-15664

Miller, D.R.; McClain, E.S.; Cliffel, D.E. Electrochemical Microphysiometry Detects Cellular Glutamate Uptake J. Electrochem. Soc.  2018  volume 165,  issue 12,  G3120-G3124 

Robinson, M.T.; Armbruster, M.E.; Gargye, A.; Cliffel, D.E.; Jennings, G.K. Photosystem I Multilayer Films for Photovoltage Enhancement in Natural Dye-Sensitized Solar Cells ACS  Applied Energy Materials 2018, 1(2), 301-305.

Robinson, M.T.; Cliffel, D.E.; Jennings, G.K. An Electrochemical Reaction-​Diffusion Model of the Photocatalytic Effect of Photosystem I Multilayer Films Journal of Physical Chemistry B 2018, 122, 1, 117-125.

Gnecco, J.S.; Anders, A.P.; Cliffel. D.; Pensabene, V.; Rogers, L.M.; Osteen, K.; Arnoff, D.M. Instrumenting a Fetal Membrane on a Chip as Emerging Technology for Preterm Birth Research Current Pharmaceutical Design 2017, 23(40), 6115-6124.

Robinson, M.T.; Gizze, E.A.; Mwambutsa, F.; Cliffel, D.E.; Jennings, G.K. Mediated approaches to Photosystem I-based biophotovoltaics  Current Opinion in Electrochemistry 2017, 5(1),211-217.

Travis, A.R.; Liau, V.A.; Agrawal, A.C.; Cliffel, D.E.Small gold nanoparticles presenting linear and looped Cilengitide analogues as radiosensitizers of cells expressing ανβ3 integrin Journal of Nanoparticle Research2017,19, 11, 1-9.

Davis, A.N.; Travis, A.R.; Miller, D.R; Cliffel, D.E. Multianalyte Physiological Microanalytical Devices  Annual Review of Analytical Chemistry 2017, 10, 93-111.

Gnecco, J.S.; Anders, A.P.; Cliffel, D.; Pensabene, V.; Rogers, L.M.; Osteen, K.; Aronoff, D.M. Instrumenting a Fetal Membrane on a Chip as Emerging Technology for Preterm Birth Research Current Pharmaceutical Design 2017, 23 (46)

Kimmel, D.W.; Dole, W.P.; Cliffel, D.E. Elucidation of the Role of Lectin-Like oxLDL Receptor-1 in the Metabolic Responses of Macrophages to Human oxLDL  Journal of Lipids 2017, Article ID 8479482.

Robinson, M.T.; Simons, C.E.; Cliffel, D.E.; Jennings, G.K. Photocatalytic photosystem I/PEDOT composite films prepared by vapor-phase polymerization  Nanoscale 2017, 9, 6158-6166.

Yang, S.; Robinson, M.T.; Mwambutsa, F.; Cliffel, D.E.; Jennings, G.K. Effect of Cross-linking on the Performance and Stability of Photocatalytic Photosystem I Films Electrochimica Acta 2016, 222,926-932.

Lizama-Manibusan, B.N.; Klein,S.; McKenzie, J.R.; Cliffel, D.E.; McLaughlin, B. Analysis of a Nitroreductase-Based Hypoxia Sensor in Primary Neuronal Cultures  ACS Chemical Neuroscience 2016, 7 (9), 1188-1191.

Wilburn, J.P.; Ciobanu, M.; Cliffel, D.E. Scanning Electrochemical Microscopy of Individual Pancreatic Islets  Journal of The Electrochemical Society 2016, 163 (4), H3077-H3082.

Kimmel, D.W.; Cliffel, D.E.; Rogers, L.M.; Arnoff, D. M. Prostaglandin E2 Regulation of Macrophage Innate Immunity  Chemical Research in Toxicology, 2016, 29, 19-25.

Gizzie, E.A.; Niezgoda, J.S.; Robinson, M.T.; Harris, A.G.; Jennings, G.K; Rosenthal, S.J.; Cliffel, D.E. Photosystem I-polyaniline/TiO2 solid-state solar cells: simple devices for biohybrid solar energy conversion  Energy & Environmental Science, 2015, 8, 3572-3576.

Lewis, S.A.; Wilburn, J.P.; Wellons, M.S.; Cliffel, D.E.; Lukehart, C.M. Carbon-supported AuPt and AuPd bimetallic nanocomposites as formic acid electrooxidation catalysts Physica Status Solidi A: Applications and Materials Science, 2015.

Beam, J.C.; LeBlanc, G.; Gizzie, E.A.; Ivanov, B.L.; Needell, D.; Shearer, M.J; Jennings, G.K.; Cliffel, D.E. Construction of a Semiconductor-Biological Interface for Solar Energy Conversion: p-doped Silicon/Photosystem I/Zinc Oxide Langmuir, 2015, 31(36), 10002-10007.

McKenzie, J. R.; Cognata, A.C.; Davis, A.N.; Wikswo, J.P.; Cliffel, D.E. Real-Time Monitoring of Cellular Bioenergetics with a Multi-Analyte Screen-Printed Electrode Analytical Chemistry, 2015, 87 (15), 7857-7864.

Crisostomo, D.; Peterson, R.R.; Cliffel, D.E. Effect of Ligand Charge on Electron Transfer Rates of Water Soluble Gold Nanoparticles Journal Of Physical Chemistry C, 2015, 119 (21), 11296-11300.

Gizzie, E.A.; LeBlanc, G.; Jennings, G.K; Cliffel, D.E. Electrochemical Preparation of Photosystem I – Polyaniline Composite Films for Biohybrid Solar Energy Conversion ACS Applied Materials and Interfaces, 2015, 7 (18), 9328-9335. 

Venmar KT, Kimmel DW, Cliffel DE, Fingleton B. IL4 receptor α mediates enhanced glucose and glutamine metabolism to support breast cancer growth. Biochimica et Biophysica Acta20154;1853(5):1219-1228.

Casey MC, Cliffel DE. Surface adsorption and electrochemical reduction of 2,4,6-trinitrotoluene on vanadium dioxide.Analytical Chemistry2015, 87(1):334-7.

Lima EA, Snider RM, Reiserer RS, McKenzie JR, Kimmel DW, Eklund SE, Wikswo JP, Cliffel DE. Multichamber Multipotentiostat System for Cellular Microphysiometry.Sensors and Actuators. B, Chemical2014, 204:536-543.

Darby E, LeBlanc G, Gizzie EA, Winter KM, Jennings GK, Cliffel DE. Photoactive films of photosystem I on transparent reduced graphene oxide electrodes. Langmuir: the ACS journal of surfaces and colloids201430(29):8990-4.

Leblanc, G., Gizzie, E., Yang, S., Cliffel, D. E., Jennings, G. K. Photosystem I Protein Films at Electrode Surfaces for Solar Energy Conversion. Langmuir2014, 0 (0): [Epub ahead of print].

Gunther, D., LeBlanc, G., Prasai, D., Zhang, J. R., Cliffel, D. E., Bolotin, K. I., Jennings, G. K. Photosystem I on Graphene as a Highly Transparent, Photoactive Electrode. Langmuir201329 (13): 4177-4180.

Wikswo, J. P., Block, F. E., Cliffel, D. E., Goodwin, C. R., Marasco, C. C., Markov, D. A., McLean, D. L., McLean, J. A., McKenzie, J. R., Reiserer, R. S., Samson, P. C., Schaffer, D. K., Seale, K. T., Sherrod, S. D. Engineering Challenges for Instrumenting and Controlling Integrated Organ-on-Chip Systems. IEEE Transactions on Biomedical Engineering2013, 60 (3): 682-690.

Kimmel, D. W., Dole, W. P., Cliffel, D. E. Application of multianalyte microphysiometry to characterize macrophage metabolic responses to oxidized LDL and effects of an apoA-1 mimetic. Biochemical and Biophysical Research Communications2013, 431 (2): 181-185.

Simpson, C. A., Salleng, K. J., Cliffel, D. E., Feldheim, D. L. In vivo toxicity, biodistribution, and clearance of glutathione-coated gold nanoparticles. NanoMedicine-NanoTechnology Biology and Medicine2013, 9 (2): 257-263.

Harkness, K. M., Turner, B. N., Agrawal, A. C., Zhang, Y. B., McLean, J. A., Cliffel, D. E.Biomimetic monolayer-protected gold nanoparticles for immunorecognition. Nanoscale2012, 4 (13): 3843-3851.

Harkness, K. M., Tang, Y., Dass, A., Pan, J., Kothalawala, N., Reddy, V. J., Cliffel, D. E., Demeler, B., Stellacci, F., Bakr, O. M., McLean, J. A. Ag-44(SR)(30)(4-): a silver-thiolate superatom complex. Nanoscale2012, 4 (14): 4269-4274.

McKenzie, J. R., Palubinsky, A. M., Brown, J. E., McLaughlin, B., Cliffel, D. E. Metabolic Multianalyte Microphysiometry Reveals Extracellular Acidosis is an Essential Mediator of Neuronal Preconditioning. ACS Chemical Neuroscience2012, 3 (7): 510-518.

Harry, R. S., Hiatt, L. A., Kimmel, D. W., Carney, C. K., Halfpenny, K. C., Cliffel, D. E., Wright, D. W. Metabolic Impact of 4-Hydroxynonenal on Macrophage-Like RAW 264.7 Function and Activation. Chemical Research in Toxicology2012, 25 (8): 1643-1651.

LeBlanc, G., Chen, G. P., Jennings, G. K., Cliffel, D. E. Photoreduction of Catalytic Platinum Particles Using Immobilized Multilayers of Photosystem I. Langmuir2012, 28 (21): 7952-7956.

Hiatt, L. A., McKenzie, J. R., Deravi, L. F., Harry, R. S., Wright, D. W., Cliffel, D. E. A printed superoxide dismutase coated electrode for the study of macrophage oxidative burst. Biosensors & Bioelectronics2012, 33 (1): 128-133.

Kimmel, D. W., LeBlanc, G., Meschievitz, M. E., Cliffel, D. E. Electrochemical Sensors and Biosensors. Analytical Chemistry2012, 84 (2): 685-707.

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