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Biological Sciences

Biological Sciences

Donna J. Webb, Ph.D.

Professor of Biological Sciences

Specializations

Signal Transduction Pathways that Regulate Adhesion and Cytoskeletal Dynamics in Migration and Synapse Formation, Cell biology, Neurobiology



Abstracts from PubMed

results for: Donna Webb Vanderbilt

Diggins, NL, Kang, H, Weaver, A, Webb, DJ α5β1 integrin trafficking and Rac activation are regulated by APPL1 in a Rab5-dependent manner to inhibit cell migration
Erdogan, B, Ao, M, White, LM, Means, AL, Brewer, BM, Yang, L, Washington, MK, Shi, C, Franco, OE, Weaver, AM, Hayward, SW, Li, D, Webb, DJ Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin
Diggins, NL, Webb, DJ APPL1 is a multifunctional endosomal signaling adaptor protein
Erdogan, B, Webb, DJ Cancer-associated fibroblasts modulate growth factor signaling and extracellular matrix remodeling to regulate tumor metastasis
Brown, JA, Codreanu, SG, Shi, M, Sherrod, SD, Markov, DA, Neely, MD, Britt, CM, Hoilett, OS, Reiserer, RS, Samson, PC, McCawley, LJ, Webb, DJ, Bowman, AB, McLean, JA, Wikswo, JP Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit
Yang, L, Carrington, LJ, Erdogan, B, Ao, M, Brewer, BM, Webb, DJ, Li, D Biomechanics of cell reorientation in a three-dimensional matrix under compression
Yang, J, Cumberbatch, D, Centanni, S, Shi, SQ, Winder, D, Webb, D, Johnson, CH Coupling optogenetic stimulation with NanoLuc-based luminescence (BRET) Ca sensing
Robinson, CM, Patel, MR, Webb, DJ Super resolution microscopy is poised to reveal new insights into the formation and maturation of dendritic spines
Brown, JA, Pensabene, V, Markov, DA, Allwardt, V, Neely, MD, Shi, M, Britt, CM, Hoilett, OS, Yang, Q, Brewer, BM, Samson, PC, McCawley, LJ, May, JM, Webb, DJ, Li, D, Bowman, AB, Reiserer, RS, Wikswo, JP Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor
Evans, JC, Robinson, CM, Shi, M, Webb, DJ The guanine nucleotide exchange factor (GEF) Asef2 promotes dendritic spine formation via Rac activation and spinophilin-dependent targeting
Ao, M, Brewer, BM, Yang, L, Franco Coronel, OE, Hayward, SW, Webb, DJ, Li, D Stretching fibroblasts remodels fibronectin and alters cancer cell migration
Broussard, JA, Diggins, NL, Hummel, S, Georgescu, W, Quaranta, V, Webb, DJ Automated analysis of cell-matrix adhesions in 2D and 3D environments
Jean, L, Yang, L, Majumdar, D, Gao, Y, Shi, M, Brewer, BM, Li, D, Webb, DJ The Rho family GEF Asef2 regulates cell migration in three dimensional (3D) collagen matrices through myosin II
Evans, JC, Hines, KM, Forsythe, JG, Erdogan, B, Shi, M, Hill, S, Rose, KL, McLean, JA, Webb, DJ Phosphorylation of serine 106 in Asef2 regulates cell migration and adhesion turnover
Brewer, BM, Shi, M, Edd, JF, Webb, DJ, Li, D A microfluidic cell co-culture platform with a liquid fluorocarbon separator
Jean, L, Majumdar, D, Shi, M, Hinkle, LE, Diggins, NL, Ao, M, Broussard, JA, Evans, JC, Choma, DP, Webb, DJ Activation of Rac by Asef2 promotes myosin II-dependent contractility to inhibit cell migration on type I collagen
Lin, WH, Hurley, JT, Raines, AN, Cheney, RE, Webb, DJ Myosin X and its motorless isoform differentially modulate dendritic spine development by regulating trafficking and retention of vasodilator-stimulated phosphoprotein
Shi, M, Majumdar, D, Gao, Y, Brewer, BM, Goodwin, CR, McLean, JA, Li, D, Webb, DJ Glia co-culture with neurons in microfluidic platforms promotes the formation and stabilization of synaptic contacts
Webb, DJ, Brown, CM, DeMali, KA Signals regulating adhesion dynamics
Broussard, JA, Rappaz, B, Webb, DJ, Brown, CM Fluorescence resonance energy transfer microscopy as demonstrated by measuring the activation of the serine/threonine kinase Akt