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Jon Kaas, Gertrude Conaway Vanderbilt Distinguished Chair in Social and Natural Sciences

Posted by on Wednesday, February 28, 2024 in Stories: Research.

Jon Kaas leads a world-renowned neuroscience laboratory that has led to seminal scientific contributions to understand the structure and function of the cerebral cortex. Kaas’s work has received multiple prestigious awards, including the 2021 Ralph W. Gerard Prize in Neuroscience, the highest recognition conferred by the Society for Neuroscience.

Kaas has had a groundbreaking career revealing the structure and function of the cerebral cortex, as well as the plasticity of the adultx` brain. Through decades of detailed research, Kaas mapped the cortex in nearly 30 mammalian species, from chimpanzees to hedgehogs, providing a clearer understanding of the evolution of the human brain and its capabilities. By integrating fine-grained electrophysical mapping with detailed anatomical reconstructions, his work has revealed the functional and structural organization of sensory systems, including the visual system and somatosensory system, across multiple species. Kaas also helped demonstrate that the adult brain is capable of functional reorganization following injury or motor training, helping to overturn the doctrine that plasticity was limited to early life. This work has led to more effective approaches to rehabilitation after brain damage following stroke, macular degeneration, or motor system disorders and injuries. The atlases Kaas has helped establish—identifying component structures, the inputs and outputs to those structures, and their functional topography—have laid the foundation for all studies of function, while his work showing that these maps are continuously revisable via life-long plasticity revolutionized rehabilitation strategies.