Pet parrots often outlive their owners, and Vanderbilt researchers want to know why—because uncovering the biological mechanisms behind exceptional longevity could one day help safely extend the lives of humans. With the support of a new $1.3 million grant from the W.M. Keck Foundation, Vanderbilt biologist Gianni Castiglione is taking a bold approach to aging research: reverse-engineering how birds live three to four times longer than similarly sized mammals to identify safe, effective genetic targets for human aging therapies.