December 11, 2015

Visual Transduction: A Signaling Paradigm Across Orders of Scale

Visual Transduction in Rod and Cone photoreceptor cells is one of the best quantified G-protein signaling cascades known to biologists. Here photons of light are converted by biochemical processes into a system’s response by diffusion of the 2nd messengers cGMP and Ca2+. The morphology of these photoreceptor cells is striking and both highly regulated, highly ordered. In this talk, I will present on how the partial differential equations’ techniques of Homogenization and Concentrating Capacity may be used at once to capture the effects of this geometry and especially its disparate physical scales.