The “Research News @ Vanderbilt” story can be found here.

Additional media outlets that have picked up the story are:

The Guardian

The Huffington Post

The New Statesman

Red Orbit

The Telegraph

Wired

The Independent

The award, which includes a $2,000 prize, is given for the best manuscript from those that were submitted to the journal after being presented to the previous year’s annual meeting of the society. Crooke presented the winning paper at the 2014 annual ISMICS meeting, and the award was announced at this year’s annual meeting in Berlin, Germany on June 4, 2015.

The winning paper is entitled, “A Geometric Model of the Normal Human Aortic Root and Design of a Fully Anatomic Aortic Root Graft,” and was co-authored with L. Alan Beavan and Charles D. Griffin of BioStable Science and Engineering, Inc., Domenico Mazzitelli of the German Heart Center Munich, and J. Scott Rankin of Vanderbilt University’s Department of Cardiac Surgery. It was published in the January/February 2015 issue of Innovations (Volume 10, Number 1).

The publication included an addendum comment from the journal’s editor that describes the significance of the research: “This is an interesting report from Dr. Crooke and his colleagues on a novel aortic root graft they have designed for root remodeling procedures. The graft was based on a model they developed of the normal human aortic root from high-resolution CT angiograms of 11 normal human aortas. The design incorporated 3 anatomic sinuses and commissural symmetry and was based on average 3-dimensional geometry. The hope is this design may prove useful in restoring aortic root geometry toward normal during aortic valve repair and root reconstruction procedures. The graft is envisioned to be used with an internal geometric annuloplasty ring of similar design.”

Prof. Crooke performed the mathematical modeling used as the basis for the design of the graft. For more about his work in this area, see “Mathematical Modeling Helps Patients Take HAART,” in the Fall 2012 edition of Spectrum, the Department of Mathematics newsletter.

]]>*MBE* is an international research journal focusing on new developments in the fast-growing fields of mathematical biosciences and engineering. According to the preface, the topics of the 12 articles appearing in the special issue honoring Webb “partially represent the broad areas of Glenn’s research interest.” They include

evolutionary dynamics of population growth, spatio-temporal dynamics in reaction-diﬀusion biological models, transmission dynamics of infectious diseases, modeling of antibiotic-resistant bacteria in hospitals, analysis of prion models, age-structured models in ecology and epidemiology, modeling of immune response to infections, and modeling of cancer growth.

The issue opens with two essays: “The Work of Glenn F. Webb,” by William E. Fitzgibbon (Dean, College of Technology, University of Houston and Vanderbilt University PhD in Mathematics) and “Studying Microbiology with Glenn F. Webb,” by Martin J. Blaser (Professor of Microbiology, New York University School of Medicine).

Webb, who joined the Vanderbilt Mathematics department in 1968, distinguished himself first as a pioneer in the area of nonlinear accretive operator theory and nonlinear semigroups and evolution operators. His research then turned to mathematical biology, with special interest in the spread of infectious disease and nonlinear population models.

From mathematical biology, which involves the development of general models, Webb moved to research that is more accurately described as biomedical mathematics, which is concerned with specific systems or maladies and is data driven. His continuing biomedical mathematics work is directed towards specific diseases such as HIV, influenza, drug-resistant bacteria, Alzheimer’s disease, cancer, and, most recently, the Ebola epidemics in West Africa.

The full special issue is available here.

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